^ White, Stephen D.; Bordeau, Patrick B.; Blumstein, Philippe; Ibisch, Catherine; GuaguÈre, Eric; Denerolle, Philippe; Carlotti, Didier N.; Scott, Katherine V. (1 September 1997). "Feline acne and results of treatment with mupirocin in an open clinical trial: 25 cases (1994–96)". Veterinary Dermatology. 8 (3): 157–164. doi:10.1046/j.1365-3164.1997.d01-16.x. ISSN 1365-3164.

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Acne, also known as acne vulgaris, is a long-term skin disease that occurs when hair follicles are clogged with dead skin cells and oil from the skin.[10] It is characterized by blackheads or whiteheads, pimples, oily skin, and possible scarring.[1][2][11] It primarily affects areas of the skin with a relatively high number of oil glands, including the face, upper part of the chest, and back.[12] The resulting appearance can lead to anxiety, reduced self-esteem and, in extreme cases, depression or thoughts of suicide.[3][4]
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The all-in-one, detoxifying and cleansing blend helps your skin look and feel beautifully clean, clear and completely healthy in less than a week by working from the inside. The powerful ingredients add kill acne-causing bacteria and eliminate toxins while powerful antioxidants fortify the skin to prevent future breakouts. The 7 Day Acne Detox approach has already helped thousands clear their skin, now you can get the same treatment for your skin! Read More…
The first thing you need to do to take care of your skin is to use sunscreen. The best acne treatment never includes sunbathing and staying out in the sun unprotected will not reduce the number of blackheads or whiteheads you have. It will, however, lead to more skin problems down the road and can cause a breakout or two right now. Wrinkles, age spots and even skin cancer are on the agenda of someone who decides they don’t need to protect their skin.

How to Handle It: If you've tried the usual anti-acne ingredients, like salicylic acid and benzoyl peroxide (which, we should warn you, rarely work for this), you should consider paying your dermatologist a visit. "You may need a cortisone injection or an oral medication, like an antibiotic, in addition to topical formulas," says Zeichner. He's also a fan of a prescription topical medication called Epiduo Forte Gel, since, he says, it's been shown to be effective at controlling severe acne without the help of oral treatments.
Salicylic acid is a topically applied beta-hydroxy acid that stops bacteria from reproducing and has keratolytic properties.[132][133] It opens obstructed skin pores and promotes shedding of epithelial skin cells.[132] Salicylic acid is known to be less effective than retinoid therapy.[19] Dry skin is the most commonly seen side effect with topical application, though darkening of the skin has been observed in individuals with darker skin types.[1]
Hypertrophic scars are uncommon, and are characterized by increased collagen content after the abnormal healing response.[31] They are described as firm and raised from the skin.[31][33] Hypertrophic scars remain within the original margins of the wound, whereas keloid scars can form scar tissue outside of these borders.[31] Keloid scars from acne occur more often in men and people with darker skin, and usually occur on the trunk of the body.[31]
^ Jump up to: a b c Zaenglein, AL; Graber, EM; Thiboutot, DM (2012). "Chapter 80 Acne Vulgaris and Acneiform Eruptions". In Goldsmith, Lowell A.; Katz, Stephen I.; Gilchrest, Barbara A.; Paller, Amy S.; Lefell, David J.; Wolff, Klaus (eds.). Fitzpatrick's Dermatology in General Medicine (8th ed.). New York: McGraw-Hill. pp. 897–917. ISBN 978-0-07-171755-7.
Acnepril has been considered the #1 Best Acne Treatment featuring 20 powerful and proven all-natural ingredients. With 100% All-Natural & 100% Safe ingredients, Acnepril has a competitive edge over prescription acne treatments delivering results WITHOUT the harmful side-effects! Its formula was specifically designed for those who have used topical acne treatments and have seen no results from it. Acnepril has been designed for those who have tried every topical acne treatment with no success. While most topical treatments target acne only at its surface, Acnepril attacks acne at its source, far below the surface of the skin. Loyal customers love the fact that Acnepril eliminates acne while NOT leaving behind any redness, infections, blackheads, and irritation no matter if you have dry or sensitive skin.

Salicylic Acid – One of the most common topical ingredients you can find over-the-counter, salicylic acid is generally used to reduce the appearance of acne, by reducing swelling and redness. Also known as a beta-hydroxy acid, it exfoliates your skin4 and unclogs your pores, too, but it is quite strong. You’ll only be able to find this in strengths around 2%, but it can still dry and irritate your skin, especially if yours is sensitive. The safest way to use this ingredient is according to the directions!
Antibiotics for acne, both topical and oral, used to be the top prescriptions for getting clear skin, but research has revealed that they aren’t the best option for most people today due to something called antibacterial resistance. This is where bacteria mutate, become immune to certain antibiotics, then reproduce offspring that are also immune, creating entire colonies of bacteria that can’t be killed by certain antibiotics.
If your acne is severe, painful, or refusing to get lost, you may just be beyond what an over-the-counter treatment can do. Not only can a professional set you up with the really powerful stuff, but also Fitz Patrick explains that “working closely with an aesthetician or dermatologist means you can keep tweaking a routine to make it work best for you.”
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The Body Shop Tea Tree Oil Products: Even though it’s not made in a lab, tea tree oil has been studied and proven to be a powerful anti-acne agent. The Body Shop takes advantage of this ingredient with their full line of tea tree oil products, from pure oil to face wipes to a clay mask, all containing tea tree oil. These products are best for oily skin, pimples, and cystic acne.
Some acne cleansers and face soaps have added ingredients to fight acne and improve the skin's appearance. Medicated cleansers contain acne-fighting ingredients like salicylic acid, sodium sulfacetamide, or benzoyl peroxide, which can help clear up skin while cleaning it. Salicylic acid helps clear blocked pores and reduces swelling and redness. Benzoyl peroxide exfoliates the skin and kills bacteria. Sodium sulfacetamide interferes with the growth of bacteria.

In most cases, acne products need to be used for at least 30 days before you can begin to ascertain its efficacy. Some skin and acne types may see noticeable results in a few days and end up totally clear in just a few weeks. Others may take several weeks to see the slightest change, or need to have their regimen adjusted as their skin adapts. Treating acne can often be a months-long process.


This top-of-line cleanser is one that really works amazingly for normal, combination and oily skin types. It’s a foaming face wash with 3% sulfur that makes your skin visibly clearer without drying it out. It removes blemishes, unclogs pores, draws out impurities all while calming redness and reducing excess sebum production. The sulfur in it helps to prevent future breakouts and tames even the worst acne breakouts.
For adult women, spironolactone is preferred over oral antibiotics since women with adult acne will likely have this condition at least until menopause, and starting and stopping an oral antibiotic over many years could potentially contribute to drug resistance and decreased microbial response. Spironolactone is completely safe to use on an ongoing basis once the correct dose is determined by the treating physician. It is advisable to check a potassium level at the 150mg dosing.
For female adult patients, one medication that Dr. Turner often recommends is spironolactone. Many patients consider it the “miracle drug.” When used at low doses, such as 50 to 150mg per day, the androgen hormones are not cycling so rapidly, which in turn helps to relieve cystic acne, especially located on the lower cheeks, jawline and neck regions. Interestingly, spironolactone is an older drug that has been used since the ’50s, but at different doses, it acts by a completely different mechanism. Thus, it is as though it is two completely different drugs, depending on the dose, but it has the same name. The only negative aspect of spironolactone dosing at these levels is that a woman should never get pregnant while medicating with this due to ambiguity in the fetal genitalia.
Light therapy is a treatment method that involves delivering certain specific wavelengths of light to an area of skin affected by acne. Both regular and laser light have been used. When regular light is used immediately following the application of a sensitizing substance to the skin such as aminolevulinic acid or methyl aminolevulinate, the treatment is referred to as photodynamic therapy (PDT).[10][129] PDT has the most supporting evidence of all light therapies.[78] Many different types of nonablative lasers (i.e., lasers that do not vaporize the top layer of the skin but rather induce a physiologic response in the skin from the light) have been used to treat acne, including those that use infrared wavelengths of light. Ablative lasers (such as CO2 and fractional types) have also been used to treat active acne and its scars. When ablative lasers are used, the treatment is often referred to as laser resurfacing because, as mentioned previously, the entire upper layers of the skin are vaporized.[140] Ablative lasers are associated with higher rates of adverse effects compared with nonablative lasers, with examples being postinflammatory hyperpigmentation, persistent facial redness, and persistent pain.[8][141][142] Physiologically, certain wavelengths of light, used with or without accompanying topical chemicals, are thought to kill bacteria and decrease the size and activity of the glands that produce sebum.[129] As of 2012, evidence for various light therapies was insufficient to recommend them for routine use.[8] Disadvantages of light therapy can include its cost, the need for multiple visits, time required to complete the procedure(s), and pain associated with some of the treatment modalities.[10] Various light therapies appear to provide a short-term benefit, but data for long-term outcomes, and for outcomes in those with severe acne, are sparse;[76][143] it may have a role for individuals whose acne has been resistant to topical medications.[10] A 2016 meta-analysis was unable to conclude whether light therapies were more beneficial than placebo or no treatment, nor how long potential benefits lasted.[144] Typical side effects include skin peeling, temporary reddening of the skin, swelling, and postinflammatory hyperpigmentation.[10]
Benzoyl peroxide is one of the most popular acne medications available, and it works especially well for pimples because it kills the bacteria that causes them. It works by bringing oxygen under the skin, killing the particular type of bacteria associated with acne, known as p. acnes. P. acnes are anaerobic, meaning they can’t live where there is oxygen, so benzoyl peroxide is a great way to kill bacteria under the skin instantaneously1. This medication can often eradicate acne if used in the right dosage and in the right way.

According to Dr. Bailey, it’s not enough to have a facial cleanser designed for acne-prone skin. Half the battle is properly washing your face. Here’s what she recommends: “First, wet your face with warm water, then lather your cleanser over all of your facial skin. Depending on your skin type, you can use your fingers, an exfoliating cloth or a sonic skin-cleansing brush system. Rinse well with warm water to remove the lather entirely. Some of the important acne cleanser ingredients will stay behind, but the cleanser’s foaming agents, as well as built-up oil, dead cells, products and bacteria, will be rinsed off of your skin.”


Acrokeratosis paraneoplastica of Bazex Acroosteolysis Bubble hair deformity Disseminate and recurrent infundibulofolliculitis Erosive pustular dermatitis of the scalp Erythromelanosis follicularis faciei et colli Hair casts Hair follicle nevus Intermittent hair–follicle dystrophy Keratosis pilaris atropicans Kinking hair Koenen's tumor Lichen planopilaris Lichen spinulosus Loose anagen syndrome Menkes kinky hair syndrome Monilethrix Parakeratosis pustulosa Pili (Pili annulati Pili bifurcati Pili multigemini Pili pseudoannulati Pili torti) Pityriasis amiantacea Plica neuropathica Poliosis Rubinstein–Taybi syndrome Setleis syndrome Traumatic anserine folliculosis Trichomegaly Trichomycosis axillaris Trichorrhexis (Trichorrhexis invaginata Trichorrhexis nodosa) Trichostasis spinulosa Uncombable hair syndrome Wooly hair Wooly hair nevus
The cleanser and powerful acne treatment in a single formula are designed to treat and prevent breakouts in just one easy step. It’s a deep-cleaning, oil-free formula for cleansing deep into your pores to help anyone, with any skin type, get rid of acne. With only 2% salicylic acid, this gentle formula has special skin soothers that help prevent irritation and over-drying, leaving your skin feeling soft and smooth without the oiliness.
Tretinoin: As we said above, tretinoin (common brand name: Retin-A) is a synthetic retinoid, but it is stronger than some of the other options, and its cousin, isotretinoin, is even stronger. Isotretinoin, better known as Accutane, is an oral synthetic retinoid typically only prescribed for very severe cases of cystic acne because it can cause intense side effects and is a powerful teratogen, meaning it causes birth defects. However, after taking isotretinoin for several months, many people never need to do any serious acne treatment again, so for some, it is well worth the side effects.
Acne usually improves around the age of 20, but may persist into adulthood.[75] Permanent physical scarring may occur.[19] There is good evidence to support the idea that acne and associated scarring negatively affect a person's psychological state, worsen mood, lower self-esteem, and are associated with a higher risk of anxiety disorders, depression, and suicidal thoughts.[3][30][50] Another psychological complication of acne vulgaris is acne excoriée, which occurs when a person persistently picks and scratches pimples, irrespective of the severity of their acne.[61][155] This can lead to significant scarring, changes in the affected person's skin pigmentation, and a cyclic worsening of the affected person's anxiety about their appearance.[61] Rare complications from acne or its treatment include the formation of pyogenic granulomas, osteoma cutis, and solid facial edema.[156] Early and aggressive treatment of acne is advocated by some in the medical community to reduce the chances of these poor outcomes.[4]
How to Handle It: Consider salicylic acid your secret weapon. "This beta hydroxy acid helps remove excess oil and exfoliate dead cells from the skin's surface to keep pores clear," says Zeichner. Try Clinique's Acne Solution Clearing Gel, a two-time Best of Beauty winner that packs both salicylic acid and sea whip extract — an ingredient with skin-soothing properties — to help counteract the dryness sometimes caused by salicylic acid. The formula does double duty: It works as a spot treatment for mild to moderate acne and as a nightly allover treatment for pimple prevention. And since it dries clear, you can wear it to fight zits whenever, wherever.

Dry Skin – Skin that doesn’t produce enough sebum, so it doesn’t retain moisture well and dries out. Dry skin tends to crack, peel, and become itchy, flaky, irritated or inflamed easily. Acne is caused by dead skin cells and bacteria clogging pores, while dryness tightens the pores to clog them further. The best acne face washes should exfoliate your skin, but shouldn’t dry it out further.
If you have oily, tight skin and tend to get age spots or sun spots, try an exfoliant made with glycolic acid right after you cleanse your skin, no more than 4 or 5 times a week. Aveeno Positively Radiant Cleansing Pads provides just a “dab” of exfoliant that will help lighten the spots without irritating your skin (which over the long run would create new brown spots).

Benzoyl peroxide is an antibacterial ingredient, and it’s very effective at killing the P. acnes bacteria that causes breakouts. But benzoyl isn’t without its downsides. The leave-on creams and cleansing treatments can dry out sensitive skin types and bleach clothing if you aren’t careful. Board-certified dermatologist Eric Meinhardt, M.D., previously told SELF that it's best to stick to formulations that have no more than 2 percent of benzoyl peroxide listed on the active ingredients chart; stronger concentrations are harder on your skin without being any tougher on bacteria.
Even though scientists know how pimples and blackheads are formed, they are still not sure what causes you to have a body full of blemishes and the guy sitting next to you not to have a single spot on his face? It’s probably related to hereditary factors. If your parents dealt with acne when they were younger, you’re more likely to struggle with acne, too.
I get asked all the time about my favorite organic skin care products. It seems everyone is worried about putting toxins in and on their bodies. So for cleansers, I recommend Dr. Hauschka's Cleansing Cream. Organic and void of chemicals, the Dr. Hauschka line is super popular among those concerned with healthy skin. So what's in this magic cleanser? Sweet almond meal and extracts of anthyllis, calendula, chamomile and St. John's wort. This cleanser gently exfoliates while adding moisture to skin, which makes it great for aging skin, dry skin and combination skin.

Glycolic acid is another chemical exfoliant that dissolves the structural lipids that hold dead skin cells and bind them to the surface. But aside from this, studies have also shown that glycolic acid effectively encourages and stimulates the production of collagen and elastin, restoring damaged skin faster and reducing signs of environmental damage with continuous use.
PanOxyl Acne Foaming Wash: This product is marketed for facial acne, but we recommend using on pesky body acne instead. PanOxyl uses benzoyl peroxide, a highly effective acne-fighting ingredient that we’ll describe more just below, but at a concentration that is much too high to be used on your face. Most PanOxyl products contain 10% benzoyl peroxide, which will likely cause peeling and burning on your face, but could be the perfect solution for back or butt acne.
In 2015, acne was estimated to affect 633 million people globally, making it the 8th most common disease worldwide.[9][17] Acne commonly occurs in adolescence and affects an estimated 80–90% of teenagers in the Western world.[18][19][20] Lower rates are reported in some rural societies.[20][21] Children and adults may also be affected before and after puberty.[22] Although acne becomes less common in adulthood, it persists in nearly half of affected people into their twenties and thirties and a smaller group continue to have difficulties into their forties.[2]
Harsh soaps have ingredients that strip your skin of oil will put anyone at risk of pimples and clogged pores due to dry, tightened skin. Almost all body washes, no matter how gentle they claim to be, are designed to remove excess oils from your body quickly and easily. That includes removing dirt and oil from around tougher bodily hairs and pores. But the skin and hair on your face is nothing like the rest of your body. Facial skin is thinner than body skin, even though it has more sebaceous glands (glands that secrete sebum). This makes it more tender, more prone to acne and even more susceptible to aging. Thus, it has to be treated differently than the rest of your body.
Some people use natural treatments like tea tree oil (works like benzoyl peroxide, but slower) or alpha hydroxy acids (remove dead skin and unclog pores) for their acne care. Not much is known about how well many of these treatments work and their long-term safety. Many natural ingredients are added to acne lotions and creams. Talk to your doctor to see if they’re right for you.

If you have oily, tight skin and tend to get age spots or sun spots, try an exfoliant made with glycolic acid right after you cleanse your skin, no more than 4 or 5 times a week. Aveeno Positively Radiant Cleansing Pads provides just a “dab” of exfoliant that will help lighten the spots without irritating your skin (which over the long run would create new brown spots).
Antibiotics are frequently applied to the skin or taken orally to treat acne and are thought to work due to their antimicrobial activity against P. acnes and their ability to reduce inflammation.[19][81][87] With the widespread use of antibiotics for acne and an increased frequency of antibiotic-resistant P. acnes worldwide, antibiotics are becoming less effective,[81] especially macrolide antibiotics such as topical erythromycin.[15][87] Commonly used antibiotics, either applied to the skin or taken orally, include clindamycin, erythromycin, metronidazole, sulfacetamide, and tetracyclines such as doxycycline and minocycline.[46] When antibiotics are applied to the skin, they are typically used for mild to moderately severe acne.[19] Antibiotics taken orally are generally considered to be more effective than topical antibiotics, and produce faster resolution of inflammatory acne lesions than topical applications.[1] Topical and oral antibiotics are not recommended for use together.[87]
Dapsone is a topical gel medicine sold under the brand name Aczone for treating severe acne, and it’s perfect for people who want a low-maintenance acne treatment plan. Unlike many of the best acne medications, dapsone only needs to be applied once daily, and it is the only medications most people will need, though it’s always good to include a face wash and moisturizer in your skin care routine if possible. Dapsone can function on its own because it is both antibacterial and anti-inflammatory10, effectively taking care of two of the biggest causes of acne.

For female adult patients, one medication that Dr. Turner often recommends is spironolactone. Many patients consider it the “miracle drug.” When used at low doses, such as 50 to 150mg per day, the androgen hormones are not cycling so rapidly, which in turn helps to relieve cystic acne, especially located on the lower cheeks, jawline and neck regions. Interestingly, spironolactone is an older drug that has been used since the ’50s, but at different doses, it acts by a completely different mechanism. Thus, it is as though it is two completely different drugs, depending on the dose, but it has the same name. The only negative aspect of spironolactone dosing at these levels is that a woman should never get pregnant while medicating with this due to ambiguity in the fetal genitalia.


Many skin conditions can mimic acne vulgaris, and these are collectively known as acneiform eruptions.[27] Such conditions include angiofibromas, epidermal cysts, flat warts, folliculitis, keratosis pilaris, milia, perioral dermatitis, and rosacea, among others.[19][72] Age is one factor which may help distinguish between these disorders. Skin disorders such as perioral dermatitis and keratosis pilaris can appear similar to acne but tend to occur more frequently in childhood, whereas rosacea tends to occur more frequently in older adults.[19] Facial redness triggered by heat or the consumption of alcohol or spicy food is suggestive of rosacea.[73] The presence of comedones helps health professionals differentiate acne from skin disorders that are similar in appearance.[8] Chloracne, due to exposure to certain chemicals, may look very similar to acne vulgaris.[74]
For adult women, spironolactone is preferred over oral antibiotics since women with adult acne will likely have this condition at least until menopause, and starting and stopping an oral antibiotic over many years could potentially contribute to drug resistance and decreased microbial response. Spironolactone is completely safe to use on an ongoing basis once the correct dose is determined by the treating physician. It is advisable to check a potassium level at the 150mg dosing.

The Pore Normalizing Cleanser is designed just to cleanse, not treat, which is a good thing: The Nurse Practitioner study emphasizes the importance of washing with mild cleansers in conjunction with topical acne medications to combat or avoid excessive skin irritation. This one is water-based and fragrance-free, and uses sodium laureth sulfate (as opposed to its harsh cousin sodium lauryl sulfate) to eliminate any chance for irritation.
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The earliest pathologic change is the formation of a plug (a microcomedone), which is driven primarily by excessive growth, reproduction, and accumulation of skin cells in the hair follicle.[1] In normal skin, the skin cells that have died come up to the surface and exit the pore of the hair follicle.[10] However, increased production of oily sebum in those with acne causes the dead skin cells to stick together.[10] The accumulation of dead skin cell debris and oily sebum blocks the pore of the hair follicle, thus forming the microcomedone.[10] This is further exacerbated by the biofilm created by P. acnes within the hair follicle.[44] If the microcomedone is superficial within the hair follicle, the skin pigment melanin is exposed to air, resulting in its oxidation and dark appearance (known as a blackhead or open comedo).[1][10][19] In contrast, if the microcomedone occurs deep within the hair follicle, this causes the formation of a whitehead (known as a closed comedo).[1][10]
P. acnes also provokes skin inflammation by altering the fatty composition of oily sebum.[44] Oxidation of the lipid squalene by P. acnes is of particular importance. Squalene oxidation activates NF-κB (a protein complex) and consequently increases IL-1α levels.[44] Additionally, squalene oxidation leads to increased activity of the 5-lipoxygenase enzyme responsible for conversion of arachidonic acid to leukotriene B4 (LTB4).[44] LTB4 promotes skin inflammation by acting on the peroxisome proliferator-activated receptor alpha (PPARα) protein.[44] PPARα increases activity of activator protein 1 (AP-1) and NF-κB, thereby leading to the recruitment of inflammatory T cells.[44] The inflammatory properties of P. acnes can be further explained by the bacterium's ability to convert sebum triglycerides to pro-inflammatory free fatty acids via secretion of the enzyme lipase.[44] These free fatty acids spur production of cathelicidin, HBD1, and HBD2, thus leading to further inflammation.[44]
Skin type, tone, and condition vary from person to person. That explains why what worked for your best friend hasn’t helped you at all. If you are at the end of your rope with your acne and find that it is affecting your life, you really should see a dermatologist before struggling to find a new treatment. A dermatologist might still have to try a few different approaches, but they are trained to get through the process quicker. However, if your acne hasn’t caused you serious problems yet, visiting a dermatologist can be a time-consuming and expensive option. This is why many doctors say mild- to moderate- acne can be treated with over-the-counter products.
Laser Acne Treatments Successfully used to treat a wide variety of skin lesions in adults and children, advanced laser technology is now proving to be a powerful weapon in the battle against acne and acne scars. Laser treatment is designed to gently target and reduce the redness associated with inflammatory acne and acne scars. The laser can reduce ...
For those with acne-prone skin, it can be tough finding a sunscreen that doesn’t clog pores and meshes well with your skincare regimen. Oily sunscreens often lead to breakouts. In addition to the wash, toner, moisturizer and treatments, the Clear Start kit includes an acne-safe (read: oil-free) sunscreen in its lineup — perfect for those wanting the best of both worlds in avoiding all types of red faces.
Acne vulgaris Acne conglobata Acne miliaris necrotica Tropical acne Infantile acne/Neonatal acne Excoriated acne Acne fulminans Acne medicamentosa (e.g., steroid acne) Halogen acne Iododerma Bromoderma Chloracne Oil acne Tar acne Acne cosmetica Occupational acne Acne aestivalis Acne keloidalis nuchae Acne mechanica Acne with facial edema Pomade acne Acne necrotica Blackhead Lupus miliaris disseminatus faciei
Dr. Turner and her staff can offer many effective acne treatments. Before recommending a treatment plan, many factors are considered, including your gender, age and the severity of your condition. For women, other considerations are whether you are pregnant, nursing or trying to become pregnant. Before starting any treatment, be sure to tell Dr. Turner if any of these apply. This information will help her to create an appropriate treatment plan.
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