Oral isotretinoin is very effective. But because of its potential side effects, doctors need to closely monitor anyone they treat with this drug. Potential side effects include ulcerative colitis, an increased risk of depression and suicide, and severe birth defects. In fact, isotretinoin carries such serious risk of side effects that all people receiving isotretinoin must participate in a Food and Drug Administration-approved risk management program.


While a few people suffer from acne that is so severe it requires a medical prescription from a doctor, most people with mild to medium acne problems can find decent over-the-counter treatments that really work. The first key to getting your acne cleanser right is to know what active ingredients combat your acne, and then finding an acne treatment that contains it. Here are a few of the ingredients you want to look for:
Globally, acne affects approximately 650 million people, or about 9.4% of the population, as of 2010.[157] It affects nearly 90% of people in Western societies during their teenage years, but can occur before adolescence and may persist into adulthood.[18][19][22] While acne that first develops between the ages of 21 and 25 is uncommon, it affects 54% of women and 40% of men older than 25 years of age,[46][158] and has a lifetime prevalence of 85%.[46] About 20% of those affected have moderate or severe cases.[2] It is slightly more common in females than males (9.8% versus 9.0%).[157] In those over 40 years old, 1% of males and 5% of females still have problems.[19]
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This dermatologist-tested formula is a foaming face wash that works incredibly fast. It can make skin visibly clearer in as little as 12 hours. It’s made with 2% salicylic acid, Acceladerm Technology™, and PHAs, polyhydroxy acids that open pores, improve skin moisturization and calms the skin. It unblocks pores, kills bacteria and calms and soothes the skin. This Clearasil product is guaranteed to be so good that if it doesn’t work for you, they have a 30-day money-back guarantee that you can take them up on.
Salicylic acid and azelaic acid. Azelaic acid is a naturally occurring acid found in whole-grain cereals and animal products. It has antibacterial properties. A 20 percent azelaic acid cream seems to be as effective as many conventional acne treatments when used twice a day for at least four weeks. It's even more effective when used in combination with erythromycin. Prescription azelaic acid (Azelex, Finacea) is an option during pregnancy and while breast-feeding. Side effects include skin discoloration and minor skin irritation.
Try not to sweat. Wash at least twice a day, sweating only increases acne. Properly use a cleanser. Wash your face with cool water and apply a little on your fingers. Gently massage the product into the skin with slight massage movements, then wash several times thoroughly. Do not use a sponge under any circumstances; this will only increase irritation. Pay attention not only to the face but to other parts of the bode that are prone to acne.
Complementary therapies have been investigated for treating people with acne.[150] Low-quality evidence suggests topical application of tea tree oil or bee venom may reduce the total number of skin lesions in those with acne.[150] Tea tree oil is thought to be approximately as effective as benzoyl peroxide or salicylic acid, but has been associated with allergic contact dermatitis.[1] Proposed mechanisms for tea tree oil's anti-acne effects include antibacterial action against P. acnes, and anti-inflammatory properties.[65] Numerous other plant-derived therapies have been observed to have positive effects against acne (e.g., basil oil and oligosaccharides from seaweed); however, few studies have been performed, and most have been of lower methodological quality.[151] There is a lack of high-quality evidence for the use of acupuncture, herbal medicine, or cupping therapy for acne.[150]
Retinol: Retinol is simply another word for vitamin A, sort of like how we call vitamin B7 “biotin.” It’s important that our bodies get systemic vitamin A through our diet for good vision, a strong immune system, and general organ function, but some research suggests that vitamin A could have a positive impact on the skin when applied to it directly. The problem is, regular retinol doesn’t actually do much for acne. That’s because the retinoic acid found in retinol isn’t always activated when left to its own devices. We typically have to activate the retinoic acid synthetically through the creation of various medications.

This foaming cleanser is a soap-free gel that will clear away clogged pores without drying skin out. Designed not to disturb the skin’s natural moisture balance, the formula is made with astringent lavender extract to minimize pores and balance PH, while the anti-inflammatory balm mint extract soothes inflammation, giving skin a visibly clearer appearance. It uses alpha hydroxy acids and quillaja saponaria to deep clean pores and fight acne-causing bacteria.


The proper care for problem skin should begin with a competent cleansing. Do not wash more often than 2 times a day. Too frequent washing contributes to the regular removal of sebum, which leads to its further increased secretion and provokes acne even more. The temperature of the water for washing should not be too hot, it expands the already wide pores, which only increases the production of sebum and raises the risk of acne.
Harsh soaps have ingredients that strip your skin of oil will put anyone at risk of pimples and clogged pores due to dry, tightened skin. Almost all body washes, no matter how gentle they claim to be, are designed to remove excess oils from your body quickly and easily. That includes removing dirt and oil from around tougher bodily hairs and pores. But the skin and hair on your face is nothing like the rest of your body. Facial skin is thinner than body skin, even though it has more sebaceous glands (glands that secrete sebum). This makes it more tender, more prone to acne and even more susceptible to aging. Thus, it has to be treated differently than the rest of your body.
Considerations: Side effects are generally mild and short lived. Most common, in 1-5% of people are itching, burning, stinging, and tingling. Other side effects were reported in less than 1% of people. There have been a few reports from darker skinned people of lightening of the skin. Azelaic acid has not been well studied in people with dark complexions.1
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Glycolic acid is another chemical exfoliant that dissolves the structural lipids that hold dead skin cells and bind them to the surface. But aside from this, studies have also shown that glycolic acid effectively encourages and stimulates the production of collagen and elastin, restoring damaged skin faster and reducing signs of environmental damage with continuous use.
We suggest avoiding spot treatments. “Benzoyl peroxide, when placed on red spots, can actually cause more irritation and inflammation to the area. It’s best used to prevent red bumps and pustules, and applied all over the area you want to treat,” said Townsend, who was also quick to naysay a spot-treat-only approach: “Acne affects all of the pores. If someone is going to spot treat against my advice, I still suggest they spot treat one day and treat the whole face the next.”

Properly selected face cleanser will help rid your skin of bacteria that clog pores and multiply in them. High-quality face cleaning also removes dead skin cells, making acne treatment more effective. It will take a strong but gentle remedy to remove dirt without new irritations. Therefore, you should avoid abrasive scrubs and soaps for the face, which can deprive the skin of its natural oils and may cause the painful irritation.
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